1. 代表性科研项目 (1) 地龙中具有抗帕金森病活性的多肽成分研究与开发,四川省重点研发项目,2023.1–2024.12。 (2) 表面展示技术用于药用植物中降糖活性成分的研究,四川省应用基础重点研究项目,2017.1–2019.12。 (3) 用磁性纳米粒子固相萃取技术“垂钓”中药中的活性成分,国家自然科学基金, 2008.1–2010.12。 2. 代表性学术论文(通讯作者) (1) Polyphenolic glycosides with unusual four-membered ring possessing anti-Parkinson’s disease potential from black wolfberry.Phytochemistry, 2023, 213: 1137752. (2) Screening of monoamine oxidase B Inhibitors fromFragaria nubicolaby ligand fishing and their neuroprotective effects.Journal of Agricultural and Food Chemistry, 2023, 71: 512–521. (3) Ligand fishing based on cell surface display of enzymes for inhibitor screening,Analytica Chimica Acta, 2021, 1156: 338359. (4) Fast identification of lipase inhibitors in oolong tea by using lipase functionalised Fe3O4 magnetic nanoparticles coupled with UPLC–MS/MS,Food Chemistry, 2015, 173: 521-526. (5) Covalent immobilization of porcine pancreatic lipase on carboxyl-activated magnetic nanoparticles: Characterization and application for enzymatic inhibition assays, Materials Science and Engineering: C, 2014, 38: 278-285. 3. 授权专利(第一发明人) (1) 一种具有PINK1激酶激动活性的多肽及其应用。专利号:ZL202111571354.8。 (2) 黑果枸杞在制备抗神经退行性疾病药物中的应用。专利号:ZL2022102404673.9。 (3) 一种鸡蛋中氟虫腈及其代谢物的净化和检测方法。专利号:ZL202010462929.1。 |